Exposed to HIV? Here’s What to Do Within the First 72 Hours

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If you think you've been exposed to HIV, every second counts. Whether the exposure happened through unprotected sex, a needle stick, or another high-risk situation, it's essential to act fast.

Emergency HIV treatment is available, effective, and time-sensitive—and knowing what to do can make all the difference.

At McGregor Clinic, we offer immediate, compassionate care for those in need of HIV exposure treatment. Here’s what you should know and do in the first critical hours after possible exposure.

When You Should Start PEP, and Why Timing Is Critical

The most effective emergency HIV treatment available is PEP or Post-Exposure Prophylaxis. It’s a short-term medication regimen designed to prevent HIV infection after recent exposure.

What is PEP?

PEP is a 28-day course of antiretroviral medications taken once or twice daily. It works by stopping the virus from taking hold in your body. But for it to work, timing is crucial.

When Should You Start?

You must begin PEP within 72 hours of exposure. The sooner you start, the more effective it is; ideally within the first 2 to 4 hours.

Waiting beyond 72 hours dramatically reduces the chances that the medication will prevent infection.

Who Should Get PEP?

You may need HIV exposure treatment if:

  • You had unprotected sex with someone who is HIV-positive or whose status is unknown
  • You shared needles or injection equipment
  • You experienced sexual assault
  • You had a needle-stick injury in a healthcare setting

If any of these apply to you, do not wait! 

Visit your nearest emergency care center or an HIV-specialized clinic like The McGregor Clinic for emergency treatment options.

What to Expect When You Seek Emergency HIV Treatment

  1. Immediate Evaluation: A healthcare provider will assess your risk, review the timing, and test for HIV and other infections.

  2. Prescription for PEP: If you're within the 72-hour window, you’ll begin the medication regimen right away.

  3. Follow-Up Care: You’ll return for HIV testing at 4 to 6 weeks, 3 months, and sometimes at 6 months post-exposure. This helps confirm that the treatment was effective.

  4. Counseling and Support: Emotional support and prevention education are also part of the care process.

At The McGregor Clinic, we provide confidential, judgment-free support for everyone—no matter the reason for your exposure or your background.

Tips for Safe and Effective Recovery

  • Take Every Dose: Missing even one dose can reduce the effectiveness of PEP. Set reminders and build a routine.
  • Avoid Further Exposure: Use protection and take precautions while on treatment.
  • Get Retested: Follow your provider’s schedule for follow-up HIV testing.
  • Ask Questions: Our team is here to support you—not just medically, but emotionally and mentally too.

Don’t Wait; Seek Emergency HIV Treatment Now

If you’ve had a potential HIV exposure, acting fast can protect your health.

At McGregor Clinic, we’re ready to provide immediate, compassionate care and get you started on PEP as quickly as possible. Our team is here to support you, every step of the way.

Read more about our emergency treatment or contact us directly to get the help you need today. 

25 Years Serving Our Communities

The McGregor Clinic

Office: (239) 334-9555
Fax number: 239-334-2832
Address: 3487 Broadway Fort Myers, FL 33901
Service Hours: 
Monday – Thursday: 8:30am-5:00pm
Friday: 8:30am-12:00pm
Call (239) 334-9555

Prevention & Community Services Clinic

• Office: (239) 208-8035
• Fax number: 239-334-2832
• Address: 2070 Carrell Rd, Suite B Fort Myers, FL 33901
Service Hours: 
Monday - Thursday: 9:00am-11:30am and 1:00pm-3:00pm
Friday: 9:00am-11:30am
Call (239) 334-9555

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